| Trends in pregnancy outcomes in Malawian adolescents receiving antimalarial and hematinic supplements. | |
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MedLine Citation:
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PMID: 20528200 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To describe pregnancy outcomes of adolescent and adult primigravidae receiving antimalarials and hematinic supplementation and compare findings with a survey in this area a decade earlier. DESIGN: Cross-sectional surveys in intervention and control sites. SETTING: Community, antenatal and delivery facilities in Chikwawa, Malawi. A rural area with year round malaria transmission. METHODS: Data on antenatal attendance, uptake of intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP), birthweight, malaria, anaemia, for 2,152 primigravidae. OUTCOME MEASURES: Place of delivery, anaemia, malaria, birthweight. RESULTS: Fewer adolescent than adult primigravidae received >or=2 IPTp-SP doses (66 vs. 77.2%, p < 0.001), although more attended for two or more antenatal visits (92.0 vs. 76.7%, p < 0.001). Only 24.1% of adolescent primigravidae attended for hospital delivery. Women resident in intervention sites receiving IPTp-SP community distribution were more likely to choose a community delivery (p < 0.01), and have higher uptake of IPTp-SP (p = 0.036) than women not resident in these villages. Postnatal malaria prevalence was low and did not differ by age or place of delivery. Postnatal anaemia and low birthweight prevalence were higher in adolescents with community deliveries. Maternal anaemia and low birthweight prevalence were lower amongst adolescents in this study compared to estimates from the same population a decade previously. CONCLUSIONS: Adolescents had higher anaemia risk, lower IPTp-SP uptake than adults and under a quarter had a hospital delivery. Pregnancy outcomes improved compared to the survey a decade earlier. Monitoring and surveillance is required to reinforce to policy makers the need to improve adolescent coverage for available interventions. |
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Authors:
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Kelias Msyamboza; Emma Savage; Gertrude Kalanda; Peter Kazembe; Sabine Gies; Umberto D'Alessandro; Bernard J Brabin |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta obstetricia et gynecologica Scandinavica Volume: 89 ISSN: 1600-0412 ISO Abbreviation: Acta Obstet Gynecol Scand Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-19 Completed Date: 2010-08-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370343 Medline TA: Acta Obstet Gynecol Scand Country: England |
Other Details:
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Languages: eng Pagination: 1011-6 Citation Subset: IM |
Affiliation:
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Malaria Alert Centre, College of Medicine, Blantyre, Malawi. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Anemia / epidemiology Antimalarials / therapeutic use* Cross-Sectional Studies Delivery, Obstetric Drug Combinations Female Ferrous Compounds / therapeutic use Folic Acid / therapeutic use Health Surveys Hematinics / therapeutic use* Hospitals / utilization Humans Infant, Low Birth Weight Infant, Newborn Malaria / prevention & control Malawi Pregnancy Pregnancy Complications, Infectious / prevention & control Pregnancy Outcome* Prenatal Care / utilization Pyrimethamine / therapeutic use Rural Health Services Rural Population Sulfadoxine / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Antimalarials; 0/Drug Combinations; 0/Ferrous Compounds; 0/Hematinics; 2447-57-6/Sulfadoxine; 37338-39-9/sulfadoxine-pyrimethamine; 58-14-0/Pyrimethamine; 59-30-3/Folic Acid; 7720-78-7/ferrous sulfate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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