Document Detail

Trends in induction of labour, 1998-2007: a population-based study.
MedLine Citation:
PMID:  20070707     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Increasing rates of induction have been reported in the UK, the USA, Canada and Australia since the early 1990s; however, there is a lack of population-based studies on trends and pharmacological management of induction of labour. AIMS: To determine population trends in induction of labour and predictors of failed induction (in caesarean section, specifically for failure to progress with cervix dilation < or =3 cm). METHODS: Trends in induction were determined for women in NSW who laboured at > or = 32 weeks from 1998 to 2007 (N = 739 904). To determine the predictors of failed induction, 92 359 deliveries of live singletons for whom linked birth and hospital data were available (2001-2005) were examined using logistic regression analysis. RESULTS: The rate of induction increased over the decade from 25.3 to 29.1%; however, among those induced with prostaglandin alone, it decreased from 33.5 to 23.8%. Oxytocin alone was the most commonly used labour induction agent overall (51%) and in most population subgroups. The predictors of failed induction in both nullipara and multipara included increasing maternal age, pre-term and post-term birth and the use of prostaglandin or mechanical methods of induction (neither oxytocin nor prostaglandin). CONCLUSIONS: The pharmacological agents used for induction of labour have changed over the past decade. An important area for future research is to investigate how the dosage of oxytocin and prostaglandin affects pregnancy outcomes.
N M Mealing; C L Roberts; J B Ford; J M Simpson; J M Morris
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Australian & New Zealand journal of obstetrics & gynaecology     Volume:  49     ISSN:  1479-828X     ISO Abbreviation:  Aust N Z J Obstet Gynaecol     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-01-14     Completed Date:  2010-05-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0001027     Medline TA:  Aust N Z J Obstet Gynaecol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  599-605     Citation Subset:  IM    
The Kolling Institute of Medical Research, University of Sydney, Sydney, New South Wales, Australia.
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MeSH Terms
Cesarean Section
Labor Stage, First
Labor, Induced / statistics & numerical data*
New South Wales / epidemiology
Oxytocics / therapeutic use
Oxytocin / therapeutic use
Pregnancy Complications / diagnosis,  epidemiology*,  therapy*
Prostaglandins / therapeutic use
Retrospective Studies
Risk Factors
Treatment Outcome
Young Adult
Reg. No./Substance:
0/Oxytocics; 0/Prostaglandins; 50-56-6/Oxytocin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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