Document Detail

Trends in the incidence and outcomes of heart failure in Ontario, Canada: 1997 to 2007.
MedLine Citation:
PMID:  22908143     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Heart failure is a leading cause of admission to hospital, but whether the incidence of heart failure is increasing or decreasing is uncertain. We examined temporal trends in the incidence and outcomes of heart failure in Ontario, Canada.
METHODS: Using population-based administrative databases of hospital discharge abstracts and physician health insurance claims, we identified 419 551 incident cases of heart failure in Ontario between Apr. 1, 1997, and Mar. 31, 2008. All patients were classified as either inpatients or outpatients based on the patient's location at the time of the initial diagnosis. We tracked subsequent outcomes through linked administrative databases.
RESULTS: The age- and sex-standardized incidence of heart failure decreased 32.7% from 454.7 per 100 000 people in 1997 to 306.1 per 100 000 people in 2007 (p < 0.001). A comparable decrease in incidence occurred in both inpatient and outpatient settings. The greatest relative decrease occurred in patients aged 85 and over. Over the study period, 1-year risk-adjusted mortality decreased from 17.7% in 1997 to 16.2% in 2007 (p = 0.02) for outpatients, with a nonsignificant decrease from 35.7% in 1997 to 33.8% in 2007 (p = 0.1) for inpatients.
INTERPRETATION: The incidence of heart failure decreased substantially during the study period. Nevertheless, the prognosis for patients with heart failure remains poor and is associated with high mortality.
Darwin F Yeung; Nicole K Boom; Helen Guo; Douglas S Lee; Susan E Schultz; Jack V Tu
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-08-20
Journal Detail:
Title:  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne     Volume:  184     ISSN:  1488-2329     ISO Abbreviation:  CMAJ     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-02     Completed Date:  2013-01-09     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  9711805     Medline TA:  CMAJ     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  E765-73     Citation Subset:  AIM; IM    
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.
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MeSH Terms
Aged, 80 and over
Heart Failure / epidemiology*,  mortality
Hospitalization / trends
Middle Aged
Ontario / epidemiology
Young Adult
Grant Support
//Canadian Institutes of Health Research

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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