Document Detail


Trends in the age adjusted mortality from acute ST segment elevation myocardial infarction in the United States (1988-2004) based on race, gender, infarct location and comorbidities.
MedLine Citation:
PMID:  19801019     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Treatment of acute ST-segment elevation myocardial infarction (STEMI) has dramatically changed over the past 2 decades. The goal of this study was to determine trends in the mortality of patients with acute STEMIs in the United States over a 16-year period (1988 to 2004) on the basis of gender, race, infarct location, and co-morbidities. The Nationwide Inpatient Sample database was used to analyze the age-adjusted mortality rates for STEMI from 1988 to 2004 for inpatients age >40. International Classification of Diseases, Ninth Revision, Clinical Modification codes consistent with acute STEMI were used. The Nationwide Inpatient Sample database contained a total of 1,316,216 patients who had diagnoses of acute STEMIs from 1988 to 2004. The mean age of these patients was 66.92 +/- 12.82 years. A total of 163,915 hospital deaths occurred during the study period. From 1988, the age-adjusted mortality rate decreased gradually for all acute STEMIs for the entire study period (in 1988, 406.86 per 100,000, 95% confidence interval 110.25 to 703.49; in 2004, 286.02 per 100,000, 95% confidence interval 45.21 to 526.84). Furthermore, unadjusted mortality decreased from 15% in 1988 to 10% in 2004 (p <0.01). This decrease was similar between the genders, among most ethnicities, and in patients with diabetes and those with congestive heart failure. However, women and African Americans had higher rates of acute STEMI-related mortality compared to men and Caucasians over the years studied. In conclusion, age-adjusted mortality from acute STEMIs has significantly decreased over the past 16 years, with persistent higher mortality rates in women and African Americans the study period.
Authors:
Mohammed-Reza Movahed; Jooby John; Mehrnoosh Hashemzadeh; M Mazen Jamal; Mehrtash Hashemzadeh
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study     Date:  2009-08-28
Journal Detail:
Title:  The American journal of cardiology     Volume:  104     ISSN:  1879-1913     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-05     Completed Date:  2009-10-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1030-4     Citation Subset:  AIM; IM    
Affiliation:
Section of Cardiology, Department of Medicine, Southern Arizona VA Health Care System, Tucson, Arizona, USA. rmovahed@email.arizona.edu
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Aged
Comorbidity / trends
Continental Population Groups*
Diabetes Mellitus, Type 2 / epidemiology*
Electrocardiography*
Female
Heart Failure / epidemiology*
Hospital Mortality / trends
Humans
Inpatients / statistics & numerical data*
Male
Myocardial Infarction / mortality*,  physiopathology
Prognosis
Retrospective Studies
Risk Factors
Sex Factors
Survival Rate / trends
United States / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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