| Trends in adult antipsychotic polypharmacy: progress and challenges in Florida's Medicaid program. | |
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MedLine Citation:
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PMID: 20099030 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied trends in antipsychotic polypharmacy over a 4 year period in order to see if a change occurred when a statewide quality improvement program aimed at reducing the practice was implemented. Antipsychotic polypharmacy prevalence rates were calculated for eight 6-month periods for enrollees with schizophrenia and schizoaffective disorder and for those with all other diagnoses. Prevalence increased from 1/2003 to 12/2004 and then declined for 4 successive 6 month periods beginning in the 1/2005-6/05 period when the program began. Piecewise linear regression results for both diagnostic groups confirmed that the change in the likelihood of antipsychotic polypharmacy during the four 6 month periods before program implementation were significantly different than during the four 6 month periods following implementation. While it is impossible to control for the effects of all variables in evaluating the impact of any system wide intervention the data suggest that the program did help to reduce the use of antipsychotic polypharmacy. |
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Authors:
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Robert J Constantine; Ross Andel; Rajiv Tandon |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-01-23 |
Journal Detail:
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Title: Community mental health journal Volume: 46 ISSN: 1573-2789 ISO Abbreviation: Community Ment Health J Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-10-28 Completed Date: 2011-01-24 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0005735 Medline TA: Community Ment Health J Country: United States |
Other Details:
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Languages: eng Pagination: 523-30 Citation Subset: IM |
Affiliation:
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Florida Mental Health Institute, University of South Florida, Tampa, USA. rconstantine@fmhi.usf.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Antipsychotic Agents / therapeutic use* Drug Utilization / statistics & numerical data, trends Female Florida Humans Male Medicaid / statistics & numerical data* Middle Aged Physician's Practice Patterns / trends* Polypharmacy* Psychotic Disorders / drug therapy* Quality Improvement Retrospective Studies United States Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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