| Trending of impedance-monitored cardiac variables: method and statistical power analysis of 100 control studies in a pediatric intensive care unit. | |
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MedLine Citation:
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PMID: 2344756 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The NCCOM3-R6 monitor continuously monitors cardiac output and five other cardiovascular variables from the thoracic electrical bioimpedance signal. We averaged data over 5-min intervals for 130 min in 100 control studies in 40 pediatric ICU patients, age 0.04 to 20.39 yr (median 1.39) and weighing 2.0 to 59.5 kg (median 8.8). For individual studies, 99% of the 5-min averages of cardiac output fell within +/- 44% of the baseline cardiac output for that study. Normal ranges were somewhat narrower for the other five variables. When we averaged data for 100 studies, 5-min interval observations for each variable did not deviate from baseline over a 2-h period (p greater than .70). With a sample size of 100 studies, we could detect a change in cardiac output of +/- 5% at the p less than .005 level with a power of 0.95. We conclude that with a sufficiently large sample size, studies employing the NCCOM3 can detect clinically significant cardiovascular changes due to pharmacologic or procedural stressors. |
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Authors:
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J J Mickell; S E Lucking; F C Chaten; E S Young |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Critical care medicine Volume: 18 ISSN: 0090-3493 ISO Abbreviation: Crit. Care Med. Publication Date: 1990 Jun |
Date Detail:
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Created Date: 1990-07-05 Completed Date: 1990-07-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0355501 Medline TA: Crit Care Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 645-50 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics, Children's Medical Center, Medical College of Virginia, Virginia Commonwealth University, Richmond. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cardiac Output Cardiography, Impedance* / instrumentation Child Exudates and Transudates Heart Rate Humans Intensive Care Units, Pediatric* Monitoring, Physiologic / instrumentation* Plethysmography, Impedance* / instrumentation Stroke Volume Thorax / pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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