| Trend of westernization of etiology and clinical characteristics of heart failure patients in Japan--first report from the CHART-2 study. | |
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MedLine Citation:
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PMID: 21436596 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Hospitalization due to acute heart failure syndrome (AHFS) is an indicator of worsened prognosis for patients with cardiovascular disease (CVD). The Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2) Study was designed to elucidate characteristics and prognosis of patients at high risk for CVD progression due to AHFS. METHODS AND RESULTS: The CHART-2 Study is a prospective observational multicenter cohort study. Patients with overt HF, structural cardiac disorder but without HF, or with coronary artery disease (CAD) have been consecutively enrolled from October 2006. As of March 2010, a total of 10,219 patients have been recruited, making the Study the largest multicenter prospective cohort of HF patients in Japan. The mean patient age was 68.2±12.3 years and male patients accounted for 69.8%. Overt HF was observed in 46.3% of patients; and 53.7% did not have HF but were at high risk for AHFS. As HF stage progressed, the prognostic risks (eg, chronic kidney disease, reduced ejection fraction, and increased B-type natriuretic peptide level) became more prominent. Compared with the previous CHART-1 study, the prevalence of ischemic etiology and risk factors (hypertension, diabetes) have increased, as in Western studies. CONCLUSIONS: This first report demonstrates the trend of westernization of ischemic etiology and clinical characteristics of HF patients in Japan, indicating the importance of appropriate management and prevention of CAD to prevent AHFS. |
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Authors:
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Nobuyuki Shiba; Kotaro Nochioka; Masanobu Miura; Haruka Kohno; Hiroaki Shimokawa; |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study Date: 2011-03-20 |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 75 ISSN: 1347-4820 ISO Abbreviation: Circ. J. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-03-28 Completed Date: 2011-08-12 Revised Date: 2012-01-09 |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 823-33 Citation Subset: IM |
Copyright Information:
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All rights are reserved to the Japanese Circulation Society. |
Affiliation:
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Department of Evidence-based Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai 980-8574, Japan. nshiba@cardio.med.tohoku.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Coronary Artery Disease / blood, complications, diagnosis, mortality, physiopathology Diabetes Complications / blood, diagnosis, mortality, physiopathology Female Heart Failure / blood, diagnosis, etiology*, mortality*, physiopathology Humans Hypertension / blood, complications, diagnosis, mortality, physiopathology Japan / epidemiology Male Middle Aged Prevalence Prognosis Prospective Studies Risk Factors Syndrome |
| Investigator | |
Investigator/Affiliation:
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Hiroaki Shimokawa / ; Mitsumasa Fukuchi / ; Toshikazu Goto / ; Tetsuya Hiramoto / ; Kanichi Inoue / ; Atsushi Kato / ; Tatsuya Komaru / ; Masatoshi Ohe / ; Nobuyo Sekiguchi / ; Nobuyuki Shiba / ; Tsuyoshi Shinozaki / ; Masafumi Sugi / ; Kenji Tamaki / ; Tetsuya Hiramoto / ; Kanichi Inoue / ; Atsushi Kato / ; Masahiko Ogata / ; Syoichi Sato / ; Masafumi Sugi / ; J Kikuchi / ; S Oyama / ; T Tajima / ; K Tamaki / ; E Nozaki / ; N Hoshi / ; M Nakagawa / ; M Hayashi / ; N Sekiguchi / ; Y Sugai / ; Y Asaumi / ; K Fukahori / ; S Takeda / ; H Endo / ; Y Kokusho / ; M Ohe / ; T Kobayashi / ; M Morita / ; K Sakurai / ; T Kagatani / ; A Sato / ; T Goto / ; T Yahagi / ; M Matsui / ; Y Tamada / ; A Fukui / ; K Takahashi / ; K Takahashi / ; K Oumi / ; K Hao / ; S Sasaki / ; A Kikuchi / ; S Suzuki / ; N Yaoita / ; K Akai / ; Y Konno / ; J Demachi / ; T Tajima / ; N Takahashi / ; Y Konno / ; N Shiba / ; M Wakayama / ; H Kanno / ; T Ishizuka / ; J Kaneko / ; M Fukuchi / ; N Shiba / ; A Sugimura / ; J Otomo / ; H Tada / ; Y Ito / ; S Komatsu / ; J Suzuki / ; D Katayose / ; S Onodera / ; T Hiramoto / ; M Chida / ; K Iwabuchi / ; M Takeuchi / ; M Takeda / ; K Yahagi / ; Y Kagaya / ; K Otsuka / ; K Komaki / ; Y Koseki / ; T Shinozaki / ; T Tanikawa / ; S Baba / ; T Tomioka / ; M Tanaka / ; N Onoue / ; M Kanazawa / ; A Kato / ; S Namiuchi / ; B H Ong / ; C Takahashi / ; T Sugie / ; H Tada / ; S Sato / ; M Fukuchi / ; M Ogata / ; K Sakurai / ; A Sugimura / ; T Tomioka / ; O Kitamukai / ; Y Fukumoto / ; K Inoue / ; S Horiguchi / ; J Koyama / ; H Shioiri / ; T Tomioka / ; T Sakuma / ; T Komaru / ; H Kato / ; K Saji / ; Y Kagaya / ; M Miura / ; T Komaru / ; N Shiba / ; S Yasuda / ; A Karibe / ; J Demachi / ; Y Fukumoto / ; J Nawata / ; K Ito / ; M Nakayama / ; K Fukuda / ; M Takeda / ; Y Wakayama / ; R Koshida / ; J Takahashi / ; M Wakayama / ; K Kumagai / ; Y Sugai / ; K Sugimura / ; M Hirose / ; K Satoh / ; Y Asaumi / ; H Tada / ; K Saji / ; T Tada / ; M Nakano / ; Y Kokusho / ; S Fukui / ; N Yamaguchi / ; Y Ito / ; R Tsuburaya / ; K Nochioka / ; Y Miura / ; J Ohashi / ; K Aizawa / ; Y Kikuchi / ; T Takii / ; M Kondo / ; K Hao / ; K Takahashi / ; Y Takagi / ; S Nakajima / ; S Tatebe / ; T Shimizu / ; S Miyamichi / ; K Noda / ; M Sugi / ; Y Yamamoto / ; Y Minatoya / ; T Tada / ; T Shiroto / ; K Fukuda / ; M Takeda / ; N Shiba / ; K Nochioka / ; M Miura / ; M Matsuki / ; S Osaki / ; D Ito / ; K Yukishita / ; Y Kidoguchi / ; M Hotta / ; H Kohno / ; Y Nakajima / ; E Yanagisawa / ; A Mori / ; M Takahashi / ; R Takeuchi / ; K Takahashi / ; S Toudera / ; M Sugaya / ; M Sato / ; C Saga / ; J Suenaga / ; M Kikuchi / ; F Mori / |
| Comments/Corrections | |
Comment In:
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Circ J. 2011;75(4):775-6
[PMID:
21436598
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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