Document Detail


Trehalose as an endogenous reserve in spores of the fungus Myrothecium verrucaria.
MedLine Citation:
PMID:  5892589     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mandels, G. R. (U.S. Army Natick Laboratories, Natick, Mass.), Rasma Vitols, and Frederick W. Parrish. Trehalose as an endogenous reserve in spores of the fungus Myrothecium verrucaria. J. Bacteriol. 90:1589-1598. 1965.-Gross analysis of Myrothecium verrucaria spores showed approximately 3% fat, 33% carbohydrate, and 9.5% nitrogen. The water-soluble carbohydrates were trehalose, glucose, mannitol, and an unidentified phosphorylated compound. Water-soluble amino acids include leucine or norleucine (or both), valine, gamma-amino-n-butyric acid, beta-amino-n-butyric acid, ergothionine, glutamic acid, glutamine, glycine, aspartic acid, asparagine, cystine, and cystathionine. Ergosterol was also present. alphaalpha-Trehalose is the major reserve (20% of the dry weight), although approximately 30% of it appeared to be at the spore surface and was released by nonlethal treatment with 0.1 n HCl. Treatment with toluene or exposure to heat sufficient to kill the spores (20 min at 60 C) caused rapid liberation of all of the trehalose. Although spores could utilize exogenous trehalose with no appreciable lag, some stimulus, such as exposure to heat (10 min at 55 C), incubation with azide, or germination on exogenous substrates, was necessary to effect utilization of trehalose reserves. Spores have trehalase, but it is apparently at the spore surface, since it is inactivated by acid treatment which does not kill the spores. The metabolic pathway for utilization of trehalose is not known, but presumably it is not mediated by trehalase. The involvement of mannitol is indicated, since it tends to increase as trehalose decreases, although the changes are not quantitatively equivalent.
Authors:
G R Mandels; R Vitols; F W Parrish
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Journal of bacteriology     Volume:  90     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1965 Dec 
Date Detail:
Created Date:  1966-03-23     Completed Date:  1966-03-23     Revised Date:  2010-09-13    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1589-98     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Amino Acids
Chemical Phenomena
Chemistry
Disaccharides / metabolism*
Hot Temperature
Hydrochloric Acid / pharmacology
Mitosporic Fungi / metabolism*
Spores
Chemical
Reg. No./Substance:
0/Amino Acids; 0/Disaccharides; 7647-01-0/Hydrochloric Acid
Comments/Corrections

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