Document Detail


Treatments for food allergy: how close are we?
MedLine Citation:
PMID:  22434517     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Food allergy continues to be a challenging health problem, with prevalence continuing to increase and anaphylaxis still an unpredictable possibility. While improvements in diagnosis are more accurately identifying affected individuals, treatment options remain limited. The cornerstone of treatment relies on strict avoidance of the offending allergens and education regarding management of allergic reactions. Despite vigilance in avoidance, accidental ingestions and reactions continue to occur. With recent advances in the understanding of humoral and cellular immune responses in food allergy and mechanisms of tolerance, several therapeutic strategies for food allergies are currently being investigated with the hopes of providing a cure or long-term remission from food allergy.
Authors:
Julie Wang; Hugh A Sampson
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Immunologic research     Volume:  54     ISSN:  1559-0755     ISO Abbreviation:  Immunol. Res.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-10-17     Completed Date:  2013-03-07     Revised Date:  2013-03-21    
Medline Journal Info:
Nlm Unique ID:  8611087     Medline TA:  Immunol Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  83-94     Citation Subset:  IM    
Affiliation:
Division of Allergy and Immunology, Department of Pediatrics, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1198, New York, NY 10029-6574, USA. Julie.wang@mssm.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Desensitization, Immunologic / methods
Food Hypersensitivity / therapy*
Helminths / immunology
Humans
Immunoglobulin E / immunology
Interleukin-5 / immunology
Medicine, Chinese Traditional
Probiotics / therapeutic use
Toll-Like Receptors / immunology
Grant Support
ID/Acronym/Agency:
AI-066738/AI/NIAID NIH HHS; AI-44236/AI/NIAID NIH HHS; K23 AI083883/AI/NIAID NIH HHS; K23 AI083883/AI/NIAID NIH HHS; RR-026134/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Interleukin-5; 0/Toll-Like Receptors; 37341-29-0/Immunoglobulin E

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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