Document Detail

Treatments of coronary artery disease improve quality of life in the long term.
MedLine Citation:
PMID:  16439926     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Cardiovascular diseases are currently the most common cause of death worldwide. This trend has been predicted to continue until 2020. The effects of treatments by bypass operation or angioplasty on the long-term health-related quality of life (HRQoL) in patients with coronary artery disease (CAD) have not been adequately studied. OBJECTIVE: To measure the HRQoL and its changes during 8 years of follow-up after a treatment intervention. METHODS: The primary study series consisted of 280 patients, of whom 100 underwent coronary artery bypass grafting (CABG), 100 had percutaneous transluminal coronary angioplasty (PTCA), and 80 were prescribed medication. At 1 year, 81 CABG patients, 74 PTCA patients, and 64 patients in the medication group responded. In the final analysis after 8 years, 63 CABG patients, 57 PTCA patients, and 34 patients in the medication group remained. HRQoL surveys were conducted 1 and 8 years after the treatment interventions. HRQoL was measured using the Nottingham Health Profile (NHP), which has been tested and evaluated in Finland. RESULTS: CABG patients had a statistically significantly better HRQoL 8 years after the operation than at baseline on the dimensions of mobility (p <.001), energy (p =.003), and pain (p =.031). PTCA patients had a statistically significantly better HRQoL 8 years after the intervention on the dimensions of emotional reactions (p =.002), pain (p =.003), mobility (p =.004), and energy (p =.005). A significant impairment on the dimension of sleep had taken place during the 8 years follow-up after PTCA (p =.018). No significant changes were seen in the HRQoL of the patients on medication at either 1 or 8 years. DISCUSSION: The need for treatment and primary and secondary prevention of CAD will increase in the future, especially in the case of high-risk patients. The present findings indicate that CABG and PTCA continue to significantly improve CAD patients' HRQoL 8 years after the intervention.
Hannele Lukkarinen; Maija Hentinen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Nursing research     Volume:  55     ISSN:  0029-6562     ISO Abbreviation:  Nurs Res     Publication Date:    2006 Jan-Feb
Date Detail:
Created Date:  2006-01-27     Completed Date:  2006-03-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0376404     Medline TA:  Nurs Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  26-33     Citation Subset:  AIM; IM; N    
Department of Nursing and Health Administration, University of Oulu, Finland.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary / adverse effects,  psychology*
Attitude to Health
Coronary Artery Bypass / adverse effects,  psychology*
Coronary Artery Disease* / psychology,  therapy
Drug Therapy / adverse effects,  psychology*
Fatigue / etiology
Follow-Up Studies
Health Status
Middle Aged
Pain, Postoperative / etiology
Prospective Studies
Quality of Life / psychology*
Sickness Impact Profile
Sleep Disorders / etiology
Social Isolation
Time Factors
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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