Document Detail


Treatment with inhaled corticosteroids improves pulmonary function in children under 2 years old with risk factors for asthma.
MedLine Citation:
PMID:  16670505     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE OF REVIEW: To report on recent studies on the effect of inhaled corticosteroids on pulmonary function in young children with asthma. RECENT FINDINGS: Inhaled corticosteroids are considered the most effective treatment for persistent asthma in children. Appropriate control of childhood asthma may prevent more serious disease or irreversible obstruction in later years. While some authors have described an improvement with the use of inhaled corticosteroids in young children, others found no clinical or functional benefit. Various studies have shown that inhaled corticosteroids ameliorate clinical outcomes, and recently a study demonstrated improvement in pulmonary function in young children with asthma. The use of different study designs may explain the lack of consistent results and disagreement regarding the efficacy of inhaled corticosteroids in these patients. SUMMARY: Based on the preponderance of evidence, treatment with inhaled corticosteroids in infants and young children with recurrent wheeze and risk factors of developing asthma appears to allow better control of the illness and improve the pulmonary function.
Authors:
Alejandro Manuel Teper; Carlos Daniel Kofman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Current opinion in allergy and clinical immunology     Volume:  6     ISSN:  1528-4050     ISO Abbreviation:  Curr Opin Allergy Clin Immunol     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-03     Completed Date:  2006-07-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100936359     Medline TA:  Curr Opin Allergy Clin Immunol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  152-4     Citation Subset:  IM    
Affiliation:
Respiratory Center, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina. ateper@intramed.net
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MeSH Terms
Descriptor/Qualifier:
Administration, Inhalation
Adrenal Cortex Hormones / administration & dosage*
Asthma / drug therapy*,  physiopathology
Humans
Infant
Infant, Newborn
Lung / physiopathology
Risk Factors
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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