Document Detail


Treatment of vasospasm by balloon angioplasty: experimental studies and clinical experiences.
MedLine Citation:
PMID:  1355284     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The vasodilation mode and degree of the invasion caused by balloon angioplasty were experimentally examined. Assessment by light microscopy and scanning electron microscopy demonstrated that the invasion to the implanted arterial wall, taken from a patient who died from vasospasm, was minimized by the use of the balloon under the condition at 1 atm, 10 times for 10 seconds. Furthermore, we applied angioplasty to eight patients who developed severe vasospasm after subarachnoid haemorrhage, and five showed improvement in neurophysiological (transcranial Doppler sonography), neuroradiological, and clinical examinations. In addition, blood vessels obtained from one patient who died 10 days after angioplasty, demonstrated similar findings to those of the experimental studies. It can be said that angioplasty will be one of the effective therapeutic methods to manage vasospasm when it is applied under the conditions mentioned above.
Authors:
Y Konishi; E Maemura; M Shiota; M Hara; K Takeuchi; I Saito
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Neurological research     Volume:  14     ISSN:  0161-6412     ISO Abbreviation:  Neurol. Res.     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1992-09-25     Completed Date:  1992-09-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7905298     Medline TA:  Neurol Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  273-81     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Kyorin University School of Medicine, Tokyo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angioplasty, Balloon*
Animals
Autopsy
Cerebral Arteries / pathology*,  ultrastructure
Dogs
Female
Humans
Ischemic Attack, Transient / etiology,  pathology,  therapy*
Male
Microscopy, Electron, Scanning
Middle Aged
Subarachnoid Hemorrhage / complications

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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