Document Detail

Treatment of vaginal intraepithelial neoplasia with laser ablation and upper vaginectomy.
MedLine Citation:
PMID:  12297712     Owner:  NLM     Status:  MEDLINE    
To assess the effectiveness of laser ablation and upper vaginectomy in the treatment of vaginal intraepithelial neoplasia (VAIN), we have reviewed the charts of 52 patients managed with laser ablation (28 patients) and upper colpectomy (24 patients). On the basis of our results, patient selection and operator skill have a significant influence on the outcome. In posthysterectomy patients with VAIN(3) at the vaginal apex, in the region of vaginal cuff scar, upper vaginectomy is the treatment of choice, while multifocal VAIN(2-3) or colposcopically well defined lesions, involving large areas of vaginal mucosa, could be successfully managed by CO(2) laser ablation.
Emmanuel Diakomanolis; Alexadros Rodolakis; Zanis Boulgaris; Georgios Blachos; Stylianos Michalas
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  54     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  2002  
Date Detail:
Created Date:  2002-09-25     Completed Date:  2002-12-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  17-20     Citation Subset:  IM    
Copyright Information:
Copyright 2002 S. Karger AG, Basel
Colposcopy and Laser Surgery Unit, 1st Department of Obstetrics and Gynecology, Alexandra Hospital, Athens University, Athens, Greece.
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MeSH Terms
Carcinoma in Situ / surgery*
Colpotomy / methods*
Laser Therapy / methods*
Middle Aged
Retrospective Studies
Vaginal Neoplasms / surgery*

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