Document Detail

Treatment of urethral sphincter mechanism incompetence in 11 bitches with a sustained-release formulation of phenylpropanolamine hydrochloride.
MedLine Citation:
PMID:  12403516     Owner:  NLM     Status:  MEDLINE    
Between 1995 and 1999, urethral sphincter mechanism incompetence was diagnosed in 11 bitches. They had been treated with phenylpropanolamine hydrochloride at the recommended dose rate, but had shown no response or had become refractory to treatment. They were treated with phenylpropanolamine hydrochloride in a sustained-release formulation combined with diphenylpyraline hydrochloride. The urinary incontinence resolved fully in six of the bitches, two of which remained continent after the treatment was withdrawn; two showed a marked improvement on daily treatment, but the other three bitches failed to respond and underwent colposuspension.
N J Bacon; O Oni; R A S White
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Veterinary record     Volume:  151     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  2002 Sep 
Date Detail:
Created Date:  2002-10-29     Completed Date:  2003-02-11     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  England    
Other Details:
Languages:  eng     Pagination:  373-6     Citation Subset:  IM    
Queen's Veterinary School Hospital, Department of Clinical Veterinary Medicine, University of Cambridge.
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MeSH Terms
Delayed-Action Preparations
Dog Diseases / drug therapy*
Phenylpropanolamine / blood,  therapeutic use*
Treatment Outcome
Urinary Incontinence / drug therapy,  veterinary*
Reg. No./Substance:
0/Delayed-Action Preparations; 14838-15-4/Phenylpropanolamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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