Document Detail

Treatment of totally occluded saphenous vein grafts using self-expanding stents.
MedLine Citation:
PMID:  12488646     Owner:  NLM     Status:  MEDLINE    
Patients with saphenous vein graft (SVG) disease represent an increasing proportion of those referred for percutaneous coronary intervention. The success of treatment of occluded SVG with percutaneous intervention has been limited by frequent occurrence of no-reflow phenomenon. Use of self-expanding stents with low pressure pre- and post-dilation may improve success by limiting embolism of atherothrombotic debris. The self-expanding stents provide a meshed design that helps to trap the atherothrombotic debris between the vessel wall and stent struts. Results with two patients are described to illustrate the proposed technique that appears to limit no-reflow during and immediately after the procedure. Adjunctive treatment with a GP IIb-IIIa inhibitor is likely to be of benefit as well. Additional studies are required to demonstrate definitively the potential benefits of this approach.
Atul Aggarwal; Edward F Terrien; Christopher M Terrien
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Publication Detail:
Type:  Case Reports; Clinical Trial; Journal Article    
Journal Detail:
Title:  Coronary artery disease     Volume:  13     ISSN:  0954-6928     ISO Abbreviation:  Coron. Artery Dis.     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-12-18     Completed Date:  2003-05-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9011445     Medline TA:  Coron Artery Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  373-6     Citation Subset:  IM    
MCHV Campus, Burlington, VT 05401, USA.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary / methods*
Coronary Angiography
Coronary Artery Bypass
Graft Occlusion, Vascular / radiography,  therapy*
Middle Aged
Saphenous Vein / transplantation*
Thrombolytic Therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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