| Treatment strategies for peripheral artery disease. | |
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MedLine Citation:
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PMID: 19527186 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Peripheral arterial disease is an underecognized manifestation of systemic atherosclerosis associated with high rates of cardiovascular morbidity and mortality. The rationale of therapy is to reduce cardiovascular risk, improve symptoms of intermittent claudication, and prevent the development of critical limb ischemia and amputation. Exercise therapy and several pharmacologic agents have been shown to improve walking distance in patients with intermittent claudication. Patients with lifestyle-interfering symptoms despite exercise, or those who progress to critical limb ischemia, frequently undergo revascularization. Endovascular techniques are commonly used in these patients. Combined pharmacological and endovascular strategies will play an increasing role in management of these patients in the future. |
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Authors:
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Andrew B McCann; Michael R Jaff |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Expert opinion on pharmacotherapy Volume: 10 ISSN: 1744-7666 ISO Abbreviation: Expert Opin Pharmacother Publication Date: 2009 Jul |
Date Detail:
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Created Date: 2009-06-16 Completed Date: 2009-10-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100897346 Medline TA: Expert Opin Pharmacother Country: England |
Other Details:
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Languages: eng Pagination: 1571-86 Citation Subset: IM |
Affiliation:
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Vascular Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ankle Brachial Index Antilipemic Agents Cardiovascular Diseases / prevention & control, therapy Cost of Illness Exercise Therapy Humans Intermittent Claudication Muscle Weakness Patient Selection Peripheral Vascular Diseases / therapy* Prognosis Quality of Life Risk Assessment Severity of Illness Index |
| Chemical | |
Reg. No./Substance:
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0/Antilipemic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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