Document Detail

Treatment strategies for peripheral artery disease.
MedLine Citation:
PMID:  19527186     Owner:  NLM     Status:  MEDLINE    
Peripheral arterial disease is an underecognized manifestation of systemic atherosclerosis associated with high rates of cardiovascular morbidity and mortality. The rationale of therapy is to reduce cardiovascular risk, improve symptoms of intermittent claudication, and prevent the development of critical limb ischemia and amputation. Exercise therapy and several pharmacologic agents have been shown to improve walking distance in patients with intermittent claudication. Patients with lifestyle-interfering symptoms despite exercise, or those who progress to critical limb ischemia, frequently undergo revascularization. Endovascular techniques are commonly used in these patients. Combined pharmacological and endovascular strategies will play an increasing role in management of these patients in the future.
Andrew B McCann; Michael R Jaff
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Expert opinion on pharmacotherapy     Volume:  10     ISSN:  1744-7666     ISO Abbreviation:  Expert Opin Pharmacother     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-16     Completed Date:  2009-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100897346     Medline TA:  Expert Opin Pharmacother     Country:  England    
Other Details:
Languages:  eng     Pagination:  1571-86     Citation Subset:  IM    
Vascular Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
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MeSH Terms
Ankle Brachial Index
Antilipemic Agents
Cardiovascular Diseases / prevention & control,  therapy
Cost of Illness
Exercise Therapy
Intermittent Claudication
Muscle Weakness
Patient Selection
Peripheral Vascular Diseases / therapy*
Quality of Life
Risk Assessment
Severity of Illness Index
Reg. No./Substance:
0/Antilipemic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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