Document Detail

Treatment strategies for fibrous dysplasia.
MedLine Citation:
PMID:  19480037     Owner:  NLM     Status:  MEDLINE    
In fibrous dysplasia (FD), growth of the lesions usually arrests around early adolescence. However, in some cases, it continues even after this period, and it is not clear under what kind of conditions this growth continues. If this continued growth could be predicted, it would provide a vital assessment tool to determine when bone contouring should be performed. We were able to find numerous reports about FD concerning surgical procedures, but only a small number included long-term postoperative follow-up. In this paper, we investigated 11 patients with FD who were available for a postoperative follow-up longer than a 10-year period. Of these 11 patients, 6 were male and 5 were female, and the mean initial assessment age was 17.9 years. Three cases were diagnosed as Albright syndrome, 3 as monostotic, and 5 as polyostotic. Regrowth after the operation occurred in 9 of the 11 patients. Among these, growth was arrested in 5 patients at the average age of 23 years, and growth is still being observed in the remaining 4 patients including 3 patients with Albright syndrome. No statistically significant difference was detected between the affected bones and the age of growth arrest, mean age of growth arrest, and sex. Consequently, we believe it is best to perform bone contouring subsequent to growth arrest other than Albright syndrome. When growth continues indefinitely in patients with the polyostotic type, as with Albright syndrome, recurrence of the disease and the resultant deformities are predicted, so complete resection and reconstructive surgery is recommended.
Takako Kusano; Shinichi Hirabayashi; Tomoaki Eguchi; Yasushi Sugawara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of craniofacial surgery     Volume:  20     ISSN:  1536-3732     ISO Abbreviation:  J Craniofac Surg     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-28     Completed Date:  2009-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9010410     Medline TA:  J Craniofac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  768-70     Citation Subset:  D    
Department of Plastic, Oral and Maxillofacial Surgery, Teikyo University School of Medicine, Itabashi-Ku, Tokyo, Japan.
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MeSH Terms
Age Factors
Bone Transplantation
Clinical Protocols
Facial Bones / surgery*
Fibrous Dysplasia of Bone / surgery*
Fibrous Dysplasia, Monostotic / surgery
Fibrous Dysplasia, Polyostotic / physiopathology,  surgery
Follow-Up Studies
Frontal Bone / surgery
Longitudinal Studies
Mandibular Diseases / surgery
Maxillary Diseases / surgery
Osteotomy / methods
Reconstructive Surgical Procedures / methods
Sex Factors
Sphenoid Bone / surgery
Treatment Outcome
Young Adult
Zygoma / surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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