Document Detail

Treatment of severe thallium intoxication.
MedLine Citation:
PMID:  9022660     Owner:  NLM     Status:  MEDLINE    
We report a successfully treated case of severe thallium intoxication. In spite of very high serum thallium (5,240 micrograms/L), symptomatology was minor and recovery complete. Prussian Blue was administered, diuresis was enhanced by intravenous fluids and a prolonged hemodialysis was started early. High blood flows (300 mL/min) and intravenous potassium chloride supplements, to mobilize thallium from the tissues, resulted in good clearances (96 to 150 mL/min). In order to prevent the well known complications, we recommend aggressive treatment of severe thallium intoxication.
M L Malbrain; G L Lambrecht; E Zandijk; P A Demedts; H M Neels; W Lambert; A P De Leenheer; R L Lins; R Daelemans
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of toxicology. Clinical toxicology     Volume:  35     ISSN:  0731-3810     ISO Abbreviation:  J. Toxicol. Clin. Toxicol.     Publication Date:  1997  
Date Detail:
Created Date:  1997-03-06     Completed Date:  1997-03-06     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  8213460     Medline TA:  J Toxicol Clin Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  97-100     Citation Subset:  AIM; IM    
Department of Nephrology-Hypertension, A.Z. Stuivenberg Antwerpen, Belgium.
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MeSH Terms
Antidotes / therapeutic use*
Ferrocyanides / therapeutic use*
Gastric Lavage
Poisoning / therapy*
Potassium Chloride / administration & dosage
Renal Dialysis
Suicide, Attempted*
Thallium / blood,  poisoning*,  urine
Reg. No./Substance:
0/Antidotes; 0/Ferrocyanides; 7440-28-0/Thallium; 7447-40-7/Potassium Chloride; TLE294X33A/ferric ferrocyanide

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