| Treatment of severe pre-eclampsia by acetyl salicylic acid. | |
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MedLine Citation:
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PMID: 2064587 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Low-dose Aspirin inhibits thromboxane A2 with minimal effects on prostacyclin and induces clinical improvements in pre-eclampsia. Two groups of pre-eclamptic women (10 in each) were treated either by low-dose acetyl salicylic acid (group I) or by conventional therapy (group II). Both groups showed a significant drop in systolic and diastolic blood pressure, a decrease in temperature, edema and albuminuria and an increase in urine volume. These effects were more significant in group I than in group II, except for the diastolic blood pressure. The obstetric progress and perinatal outcome were rather similar in both groups. These data offer a new potential therapeutic measure for the management of severe pre-eclampsia and call for further evaluation in a larger group of cases. |
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Authors:
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M Toppozada; M Khowessah; S Shaala; S Abd-Rabbo; A Zoheir |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Asia-Oceania journal of obstetrics and gynaecology / AOFOG Volume: 17 ISSN: 0389-2328 ISO Abbreviation: Asia Oceania J Obstet Gynaecol Publication Date: 1991 Mar |
Date Detail:
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Created Date: 1991-08-06 Completed Date: 1991-08-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8102781 Medline TA: Asia Oceania J Obstet Gynaecol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 19-26 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, Shatby Hospital, University of Alexandria, Egypt. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Albuminuria / drug therapy Aspirin / administration & dosage, therapeutic use* Blood Pressure / drug effects Body Temperature / drug effects Edema / drug therapy Female Humans Hypertension / drug therapy Pre-Eclampsia / drug therapy* Pregnancy Pregnancy Trimester, Third |
| Chemical | |
Reg. No./Substance:
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50-78-2/Aspirin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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