Document Detail


Treatment of severe hypertension and hypertensive crises with nifedipine.
MedLine Citation:
PMID:  3303694     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The calcium channel blocker nifedipine is an effective antihypertensive agent for the treatment of severe hypertension and hypertensive crises. It produces a prompt, predictable and consistent reduction in systemic arterial pressure with minimal adverse effects. The blood pressure reduction is inversely correlated with the pretreatment blood pressure level. Various nonparenteral administration forms-oral, sublingual, buccal and rectal-permit a versatile, noninvasive, cost-effective alternative to parenteral antihypertensive therapy and continuous hemodynamic monitoring. Blood pressure is reduced to the goal level in 98% of patients with a 10- to 20-mg dose of nifedipine. Hemodynamic changes are favorable and morbidity is uncommon.
Authors:
M C Houston
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Western journal of medicine     Volume:  146     ISSN:  0093-0415     ISO Abbreviation:  West. J. Med.     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1987-08-31     Completed Date:  1987-08-31     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0410504     Medline TA:  West J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  701-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Hemodynamics / drug effects
Humans
Hypertension / drug therapy*
Nifedipine / adverse effects,  therapeutic use*
Chemical
Reg. No./Substance:
21829-25-4/Nifedipine
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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