| Treatment of seropositive primary syphilis: an evaluation of 196 patients. | |
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MedLine Citation:
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PMID: 929349 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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One hundred seventy-five patients with primary infection with Treponema pallidum were treated with benzathine penicillin G, 2.4 million units given intramuscularly weekly for two weeks for a total of 4.8 million units. Twenty-one patients with primary syphilis who were allergic to penicillin were treated with oral tetracycline, 500 mg four times daily for 12 days for a total of 24 gm. All 196 patients had resolution of their lesions, and all were seronegative within one year. White patients presented for treatment earlier than black patients. The duration of symptoms prior to presentation for treatment was positively correlated with the height of the serologic titer in the rapid plasma reagin card test. Patients who had high titers before treatment became seronegative less rapidly than patients who had low pretreatment titers. |
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Authors:
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N J Fiumara |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Sexually transmitted diseases Volume: 4 ISSN: 0148-5717 ISO Abbreviation: Sex Transm Dis Publication Date: 1977 Jul-Sep |
Date Detail:
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Created Date: 1978-01-27 Completed Date: 1978-01-27 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 7705941 Medline TA: Sex Transm Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 92-5 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Female Humans Male Middle Aged Penicillin G Benzathine / therapeutic use* Syphilis / drug therapy*, transmission Syphilis Serodiagnosis Tetracyclines / therapeutic use* Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Tetracyclines; 1538-09-6/Penicillin G Benzathine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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