Document Detail


Treatment-resistant meningitis leading to the diagnosis of Currarino syndrome: a case report.
MedLine Citation:
PMID:  19483525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 20-day-old female infant developed fever. Sepsis evaluation revealed cerebrospinal fluid (CSF) pleocytosis and a modestly decreased CSF glucose. After 48 hours of broad-spectrum antibiotics, the infant remained febrile. Repeat CSF analysis showed increased pleocytosis and a very low glucose value. Subsequently, a rectothecal fistula and sacral abnormalities were found, leading to the diagnosis of Currarino syndrome. Parameningeal foci should be considered in treatment-resistant meningitis.
Authors:
Autumn S Kiefer; Priyanka Gupta; Salman Kirmani; Kara Schwartz; Nancy Henry; Philip R Fischer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  28     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-01     Completed Date:  2009-08-31     Revised Date:  2009-12-30    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  547-9     Citation Subset:  IM    
Affiliation:
Mayo School of Graduate Medical Education, Rochester, MN, USA. kiefer.autumn@mayo.edu
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / diagnosis*
Anal Canal / abnormalities
Anti-Bacterial Agents / therapeutic use
Antiviral Agents / therapeutic use
Constriction, Pathologic
Female
Homeodomain Proteins / genetics
Humans
Infant, Newborn
Meningitis / cerebrospinal fluid,  diagnosis,  drug therapy*
Meningocele
Rectal Fistula
Sacrum / abnormalities
Syndrome
Transcription Factors / genetics
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Antiviral Agents; 0/Homeodomain Proteins; 0/MNX1 protein, human; 0/Transcription Factors
Comments/Corrections
Comment In:
Pediatr Infect Dis J. 2010 Jan;29(1):90   [PMID:  20035210 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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