Document Detail


Treatment of renovascular hypertension by transluminal angioplasty--13 years experience in a single centre.
MedLine Citation:
PMID:  17934918     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The study is a follow-up on treatment of renovascular hypertension (RVH) with percutaneous transluminal renal angioplasty (PTRA). METHODS: Patients were screened on the basis of clinical criteria of increased probability of RVH with renography and in selected cases with renal vein renin measurements. A positive work-up suggesting a functionally important renal artery stenosis led to renal angiography and PTRA if stenosis was confirmed; in 59%, an intravascular stent was inserted. RESULTS: Outcome of treatment was classified as follows - group I: normotensive without medication; group II: with improved control of blood pressure; group III: unchanged blood pressure control. Grouping was performed immediately after treatment, at 1 month, 6 months and at the latest follow-up. One hundred-and-twenty-two patients (124 atherosclerotic and 12 fibromuscular lesions) were treated during 13 years. Immediately after PTRA the patients were grouped as follows - I: 31%, II: 59%, III: 10%. At 1 month, I: 13%, II: 72%, III: 15%; at 6 months, I: 11%, II: 74%, III: 15%, and at the latest follow-up, I: 11%, II: 78%, III: 11%. There were few significant complications, and renal function remained on average stable. CONCLUSION: PTRA is an effective treatment of RVH in patients selected by signs of a flow-restricting stenosis. Twelve percent were normotensive after angioplasty and a further 77% had better controlled hypertension. Few complications were seen and renal function was on average unchanged as measured by serum creatinine.
Authors:
Kristian A Øvrehus; Poul E Andersen; Ib A Jacobsen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Blood pressure     Volume:  16     ISSN:  0803-7051     ISO Abbreviation:  Blood Press.     Publication Date:  2007  
Date Detail:
Created Date:  2007-10-15     Completed Date:  2007-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9301454     Medline TA:  Blood Press     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  335-40     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine C, Odense University Hospital, Denmark.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Angioplasty, Balloon / adverse effects,  methods*
Blood Pressure
Creatinine / blood
Female
Follow-Up Studies
Humans
Hypertension, Renovascular / diagnosis,  therapy*
Kidney / blood supply,  physiopathology
Male
Middle Aged
Time
Treatment Outcome
Chemical
Reg. No./Substance:
60-27-5/Creatinine
Comments/Corrections
Comment In:
Blood Press. 2007;16(5):288-90   [PMID:  17934915 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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