Document Detail

Treatment recommendations for anticonvulsant drug therapy in the older patient.
MedLine Citation:
PMID:  1596599     Owner:  NLM     Status:  MEDLINE    
Seizures in older individuals are frequently due to cerebrovascular disease, though other causes, such as primary or metastic brain tumour, must be considered. Recurrence after a first seizure may be as high as 83% by 3 years, suggesting that withholding an anticonvulsant after a first seizure may not be wise. Some older patients may be more sensitive to anticonvulsant side effects, so treatment with 1 drug is encouraged, with monitoring of blood concentrations of the anticonvulsant during initiation of therapy. Interaction of anticonvulsants with other drugs is less of a problem than may be expected, but should be kept in mind. The treatment of status epilepticus should be aggressive.
P D Swanson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Drugs & aging     Volume:  2     ISSN:  1170-229X     ISO Abbreviation:  Drugs Aging     Publication Date:    1992 Mar-Apr
Date Detail:
Created Date:  1992-07-07     Completed Date:  1992-07-07     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9102074     Medline TA:  Drugs Aging     Country:  NEW ZEALAND    
Other Details:
Languages:  eng     Pagination:  95-102     Citation Subset:  IM    
University of Washington School of Medicine, Seattle.
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MeSH Terms
Aging / physiology*
Anticonvulsants / therapeutic use*
Middle Aged
Seizures / drug therapy*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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