Document Detail


Treatment of recalcitrant Darier's disease with electron beam therapy.
MedLine Citation:
PMID:  20597949     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Darier's disease (DD) is difficult to treat and has no cure. Although many modalities have been investigated, treatment options to date are largely unsatisfactory. Side-effect profiles have limited the use of many of these therapies, as has their ability to target only limited areas of disease. Furthermore, the effectiveness of most available treatments seems to be highly individualized, varying with disease severity and offering little alteration in the natural course of the disease. The present study reports a case of severe DD that was poorly responsive to known therapeutic modalities but responded to electron beam radiotherapy, and recommends this therapeutic modality for localized areas of severe, recalcitrant symptomatic disease.
Authors:
Ashley Kittridge; Christina Wahlgren; Russell Fuhrer; Matthew Zirwas; Timothy Patton
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Dermatologic therapy     Volume:  23     ISSN:  1529-8019     ISO Abbreviation:  Dermatol Ther     Publication Date:    2010 May-Jun
Date Detail:
Created Date:  2010-07-05     Completed Date:  2010-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9700070     Medline TA:  Dermatol Ther     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  302-4     Citation Subset:  IM    
Affiliation:
Lake Erie College of Osteopathic Medicine, Erie, Pennsylvania, USA.
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MeSH Terms
Descriptor/Qualifier:
Darier Disease / radiotherapy*
Electrons
Female
Humans
Middle Aged
Radiotherapy, High-Energy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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