| Treatment of primary aspergilloma of the central nervous system in a diabetic immunocompetent patient with surgical resection and voriconazole: a case report and review of the literature. | |
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MedLine Citation:
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PMID: 22194129 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Fungal infections of the central nervous system (CNS) are uncommon and occur mainly in immunocompromised patients. We describe a case of central nervous system aspergilloma without any evidence of systemic or paranasal foci in a diabetic but otherwise immunocompetent 71-year-old female treated successfully with surgical resection and medical therapy with voriconazole. Magnetic resonance imaging (MRI) after 6 months of voriconazole showed improvement and no evidence of residual or recurrent disease. Given its good CNS penetration, voriconazole along with surgical resection appears to be promising in treatment of these infections. Our case also demonstrates the importance of surgical intervention in the diagnosis and management of these atypical cases. |
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Authors:
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Robin Koshy; Prashant Malhotra |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Turkish neurosurgery Volume: 21 ISSN: 1019-5149 ISO Abbreviation: Turk Neurosurg Publication Date: 2011 |
Date Detail:
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Created Date: 2011-12-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9423821 Medline TA: Turk Neurosurg Country: Turkey |
Other Details:
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Languages: eng Pagination: 641-4 Citation Subset: IM |
Affiliation:
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North Shore University Hospital, Division of Infectious Diseases, Manhasset, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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