Document Detail


Treatment and prevention of intestinal parasite-associated disease.
MedLine Citation:
PMID:  14740770     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Since 1917, only 11 new endoparasiticides have been developed for the horse, of which five chemical classes are in common use. The selection pressure of frequent administration of deworming doses for parasite control programs has been associated with the development of resistance of small strongyle parasites to the effects of benzimidazoles and pyrantel salts. Against the background of the inevitability of the occurrence of ivermectin/moxidectin resistance, responsible use of equine anthelmintics based on the clinical pharmacology of the compounds and the biology/epidemiology of intestinal parasites is a major issue for equine clinicians. The evidence base for the recommendations for treatment and control of equine intestinal parasites is sparse, however, and few robust data exist from controlled clinical trials to validate current guidelines.
Authors:
Sandy Love
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Veterinary clinics of North America. Equine practice     Volume:  19     ISSN:  0749-0739     ISO Abbreviation:  Vet. Clin. North Am. Equine Pract.     Publication Date:  2003 Dec 
Date Detail:
Created Date:  2004-01-26     Completed Date:  2004-04-13     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8511904     Medline TA:  Vet Clin North Am Equine Pract     Country:  United States    
Other Details:
Languages:  eng     Pagination:  791-806     Citation Subset:  IM    
Affiliation:
Division of Equine Clinical Studies, Faculty of Veterinary Medicine, University of Glasgow, Bearsden Road, Glasgow, Scotland G61 8QH, UK. s.love@vet.gla.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Animals
Anthelmintics / therapeutic use*
Dose-Response Relationship, Drug
Drug Resistance
Drug Therapy, Combination
Horse Diseases / drug therapy,  prevention & control*
Horses
Intestinal Diseases, Parasitic / drug therapy,  prevention & control,  veterinary*
Strongyle Infections, Equine / drug therapy,  prevention & control*
Chemical
Reg. No./Substance:
0/Anthelmintics

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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