| Treatment of persistent knee effusions with intra-articular radioactive gold. | |
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MedLine Citation:
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PMID: 1125918 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Patients with a total of 112 chronic knee effusions unresponsive to the usual conservative methods of therapy were treated with intra-articular injections of radioactive gold and followed from 6 months to 5 years. Most patients in the study had rheumatoid arthritis but others had ankylosing spondylitis, psoriatic arthritis, intermittent hydrathrosis and undiagnosed synovitis. After 6 months 81% showed improvement. This figure diminished to approximately 70% at 1 and 2 years, 60% at 3 and 4 years and 50% at 5 years. The mose beneficial results were seen in patients with intermittent hydrarthrosis. Twelve patients with a synovial cyst and/or rupture improved. Patients with thin synovia and anatomic stage I or II disease did best, but those with stage III disease also did well. After the injection 33% of the patients had a reactive synovitis. A variable amount of radioactive material escaped from the knee to the regional lymph nodes and general circulation. |
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Authors:
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J R Topp; E G Cross; A G Fam |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Canadian Medical Association journal Volume: 112 ISSN: 0008-4409 ISO Abbreviation: Can Med Assoc J Publication Date: 1975 May |
Date Detail:
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Created Date: 1975-07-24 Completed Date: 1975-07-24 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0414110 Medline TA: Can Med Assoc J Country: CANADA |
Other Details:
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Languages: eng Pagination: 1085-9 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Arthritis, Rheumatoid / drug therapy Drug Evaluation Female Follow-Up Studies Gold Colloid, Radioactive / administration & dosage*, therapeutic use Humans Injections, Intra-Articular Joint Diseases / drug therapy*, pathology Knee Joint* Male Spondylitis, Ankylosing / drug therapy Synovitis / drug therapy Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Gold Colloid, Radioactive |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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