| Treatment of persistent glaucoma secondary to periocular corticosteroids. | |
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MedLine Citation:
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PMID: 8694104 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To describe two patients with uveitis who developed increased intraocular pressure that was unresponsive to maximum medical therapy eight and 13 months after periocular injection of triamcinolone acetonide. METHODS: Excised periocular tissue was analyzed for corticosteroid activity by gas chromatography and mass spectrometry. RESULTS: Excision of the periocular tissue, which contained visible triamcinolone acetonide, resulted in a normal intraocular pressure within 14 days in both patients. Analysis of the excised tissue disclosed residual corticosteroid in one of the two patients. CONCLUSION: Removal of periocular tissue containing injected corticosteroids may facilitate the management of patients developing increased intraocular pressure unresponsive to maximum medical therapy. |
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Authors:
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L Akduman; A E Kolker; D L Black; L V Del Priore; H J Kaplan |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of ophthalmology Volume: 122 ISSN: 0002-9394 ISO Abbreviation: Am. J. Ophthalmol. Publication Date: 1996 Aug |
Date Detail:
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Created Date: 1996-08-27 Completed Date: 1996-08-27 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370500 Medline TA: Am J Ophthalmol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 275-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO 63110-1096, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Inflammatory Agents
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adverse effects*,
therapeutic use Antihypertensive Agents / therapeutic use Child Fascia / surgery Glaucoma / chemically induced, therapy* Humans Injections Intraocular Pressure Male Middle Aged Ocular Hypertension / chemically induced, therapy Orbit / drug effects, surgery Triamcinolone Acetonide / adverse effects*, therapeutic use Uveitis / complications, drug therapy |
| Grant Support | |
ID/Acronym/Agency:
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EY02687/EY/NEI NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents; 0/Antihypertensive Agents; 76-25-5/Triamcinolone Acetonide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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