Document Detail

Treatment of patients with long-standing unexplained subfertility with in vitro fertilization.
MedLine Citation:
PMID:  10685539     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate whether IVF is an effective treatment for long-standing unexplained subfertility. DESIGN: Retrospective cohort study. SETTING: Tertiary care infertility center in a university hospital. PATIENT(S): Two hundred two couples with unexplained subfertility of 2 years' duration or more who attended the center for their first IVF attempt. INTERVENTION(S): Couples were placed on a waiting list for IVF. They received no treatment until IVF was started. MAIN OUTCOME MEASURE(S): Pregnancy rate (PR) while on the waiting list and PR after IVF treatment. RESULT(S): Complete data sets were available for 131 couples. Seventeen of 131 women became pregnant while waiting for IVF treatment (PR 0.9% per exposure cycle), whereas 45 of 119 receiving IVF treatment became pregnant (PR 17% per IVF attempt). CONCLUSION(S): IVF treatment has substantial added value over waiting and is an efficient treatment for long-standing unexplained subfertility.
P F Donderwinkel; H van der Vaart; V M Wolters; A H Simons; G Kroon; M J Heineman
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Fertility and sterility     Volume:  73     ISSN:  0015-0282     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-03-09     Completed Date:  2000-03-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  334-7     Citation Subset:  IM    
Division of Reproductive Medicine, University Hospital Groningen, The Netherlands.
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MeSH Terms
Fertilization in Vitro*
Infertility, Female / therapy*
Life Tables
Pregnancy Rate
Retrospective Studies
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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