Document Detail

Treatment of oromandibular dystonia with botulinum toxin.
MedLine Citation:
PMID:  1943423     Owner:  NLM     Status:  MEDLINE    
Botulinum toxin produces muscle weakness by inhibition of acetylcholine release at the neuromuscular junction. The toxin has been used successfully for symptomatic treatment of focal dystonias. Our experience in the use of botulinum toxin for the treatment of oromandibular dystonia in five patients is reported. Improvement following treatment was reported as marked by 1 patient, moderate by 1 patient, and mild by 3 patients. Similar improvement was noted by the examiners. One patient with mild cosmetic improvement developed significant dysphagia requiring feeding by a nasogastric tube for a 3-month period.
N Hermanowicz; D D Truong
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Laryngoscope     Volume:  101     ISSN:  0023-852X     ISO Abbreviation:  Laryngoscope     Publication Date:  1991 Nov 
Date Detail:
Created Date:  1991-12-20     Completed Date:  1991-12-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1216-8     Citation Subset:  IM    
Department of Neurology, University of Michigan, Ann Arbor.
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MeSH Terms
Botulinum Toxins / therapeutic use*
Dystonia / drug therapy*,  physiopathology
Masticatory Muscles*
Middle Aged
Reg. No./Substance:
0/Botulinum Toxins

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