Document Detail

Treatment of oral chronic graft-versus-host disease with PUVA therapy: case report and literature review.
MedLine Citation:
PMID:  9720094     Owner:  NLM     Status:  MEDLINE    
Chronic graft-versus-host disease commonly appears with oral manifestations subsequent to allogeneic bone marrow transplantation. These manifestations include leukoplakia, mucosal atrophy, erythema, ulcers, and xerostomia. Some lesions are resistant to treatment with immunosuppressive medications. Ultraviolet A irradiation therapy with oral psoralen has been shown to be effective in treating these resistant lesions. This article presents a review of the literature and a case report.
S W Redding; N S Callander; C W Haveman; D L Leonard
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  86     ISSN:  1079-2104     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-11-19     Completed Date:  1998-11-19     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  183-7     Citation Subset:  D; IM    
Department of General Dentistry, University of Texas Health Science Center, San Antonio, USA.
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MeSH Terms
Administration, Oral
Bone Marrow Transplantation / adverse effects
Drug Resistance
Erythema / drug therapy,  immunology
Graft vs Host Disease / drug therapy*
Immunosuppressive Agents / therapeutic use
Leukoplakia, Oral / drug therapy,  immunology
Middle Aged
Mouth Diseases / drug therapy*,  immunology
Mouth Mucosa / pathology
Oral Ulcer / drug therapy,  immunology
PUVA Therapy*
Photosensitizing Agents / administration & dosage,  therapeutic use
Psoralens / administration & dosage,  therapeutic use
Transplantation, Homologous
Xerostomia / drug therapy,  immunology
Reg. No./Substance:
0/Immunosuppressive Agents; 0/Photosensitizing Agents; 0/Psoralens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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