Document Detail

Treatment options for prehypertension.
MedLine Citation:
PMID:  17420669     Owner:  NLM     Status:  MEDLINE    
PURPOSE OF REVIEW: Prehypertension is a recognized stage of blood pressure but treatment standards have not yet been established. This review will focus on the treatment considerations in prehypertension.
RECENT FINDINGS: Previous approaches to prehypertensive blood pressure have focused on the role of nonpharmacologic modalities alone. The recently published Trial of Preventing Hypertension (TROPHY) is the first study of pharmacologic intervention in this category of blood pressure.
SUMMARY: TROPHY forged new territory in the area of pharmacologic treatment for prehypertension. The safety and tolerability of the angiotensin receptor blocker treatment in the trial offer a new option to clinicians attempting to avoid the ravages of hypertension in the patients they treat. Furthermore the stage is properly set for additional research in treatments for prehypertension.
Shawna D Nesbitt
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Current opinion in nephrology and hypertension     Volume:  16     ISSN:  1062-4821     ISO Abbreviation:  Curr. Opin. Nephrol. Hypertens.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-10     Completed Date:  2007-06-07     Revised Date:  2013-05-28    
Medline Journal Info:
Nlm Unique ID:  9303753     Medline TA:  Curr Opin Nephrol Hypertens     Country:  England    
Other Details:
Languages:  eng     Pagination:  250-5     Citation Subset:  IM    
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8899, USA.
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MeSH Terms
Angiotensin II Type 1 Receptor Blockers / pharmacology,  therapeutic use*
Antihypertensive Agents / pharmacology,  therapeutic use*
Benzimidazoles / therapeutic use
Blood Pressure / drug effects*
Disease Progression
Hypertension / epidemiology,  physiopathology,  prevention & control*
Life Style*
Practice Guidelines as Topic
Tetrazoles / therapeutic use
Grant Support
Reg. No./Substance:
0/Angiotensin II Type 1 Receptor Blockers; 0/Antihypertensive Agents; 0/Benzimidazoles; 0/Tetrazoles; S8Q36MD2XX/candesartan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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