Document Detail

Treatment of opioid dependence in the setting of pregnancy.
MedLine Citation:
PMID:  22640765     Owner:  NLM     Status:  MEDLINE    
Opioid dependence in the setting of pregnancy provides a distinct set of challenges for providers. Treatment plans must take into consideration psychiatric and medical comorbidities while balancing risks and benefits for the maternal-fetal dyad. Treatment is best offered through a comprehensive treatment program designed to effectively deliver opioid agonist maintenance treatment along with psychosocial and obstetric care. As misuse of prescription analgesics increases in the United States, identification of the problem in pregnancy will become more important because this misuse is expected to lead to an increased prevalence of opioid dependence in pregnancy. Buprenorphine as maintenance treatment of opioid dependence during pregnancy has promise and may offer some benefits, but more research is needed, especially regarding induction of actively addicted women during pregnancy. For the present, methadone maintenance remains the standard of care for agonist treatment of opioid dependence in pregnancy against which other treatments must be compared.
Jessica L Young; Peter R Martin
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Publication Detail:
Type:  Journal Article     Date:  2012-04-11
Journal Detail:
Title:  The Psychiatric clinics of North America     Volume:  35     ISSN:  1558-3147     ISO Abbreviation:  Psychiatr. Clin. North Am.     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-29     Completed Date:  2012-09-06     Revised Date:  2014-04-08    
Medline Journal Info:
Nlm Unique ID:  7708110     Medline TA:  Psychiatr Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  441-60     Citation Subset:  IM    
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MeSH Terms
Alcohol-Related Disorders / drug therapy,  epidemiology
Analgesics, Opioid / administration & dosage,  adverse effects,  therapeutic use*
Buprenorphine / administration & dosage,  therapeutic use*
Delivery, Obstetric / methods
Infant, Newborn
Methadone / administration & dosage,  therapeutic use*
Neonatal Abstinence Syndrome / drug therapy,  prevention & control*
Opiate Substitution Treatment / methods
Opioid-Related Disorders / diagnosis,  drug therapy*,  epidemiology
Pain Management / methods
Pregnancy Complications / diagnosis,  drug therapy*,  epidemiology
Prenatal Care / methods,  organization & administration
Prenatal Exposure Delayed Effects
Prescription Drugs / adverse effects
Self Medication
Substance Withdrawal Syndrome / prevention & control
United States / epidemiology
Reg. No./Substance:
0/Analgesics, Opioid; 0/Prescription Drugs; 40D3SCR4GZ/Buprenorphine; UC6VBE7V1Z/Methadone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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