| Treatment of opioid dependence in the setting of pregnancy. | |
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MedLine Citation:
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PMID: 22640765 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Opioid dependence in the setting of pregnancy provides a distinct set of challenges for providers. Treatment plans must take into consideration psychiatric and medical comorbidities while balancing risks and benefits for the maternal-fetal dyad. Treatment is best offered through a comprehensive treatment program designed to effectively deliver opioid agonist maintenance treatment along with psychosocial and obstetric care. As misuse of prescription analgesics increases in the United States, identification of the problem in pregnancy will become more important because this misuse is expected to lead to an increased prevalence of opioid dependence in pregnancy. Buprenorphine as maintenance treatment of opioid dependence during pregnancy has promise and may offer some benefits, but more research is needed, especially regarding induction of actively addicted women during pregnancy. For the present, methadone maintenance remains the standard of care for agonist treatment of opioid dependence in pregnancy against which other treatments must be compared. |
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Authors:
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Jessica L Young; Peter R Martin |
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Publication Detail:
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Type: Journal Article Date: 2012-04-11 |
Journal Detail:
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Title: The Psychiatric clinics of North America Volume: 35 ISSN: 1558-3147 ISO Abbreviation: Psychiatr. Clin. North Am. Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-05-29 Completed Date: 2012-09-06 Revised Date: 2013-04-26 |
Medline Journal Info:
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Nlm Unique ID: 7708110 Medline TA: Psychiatr Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 441-60 Citation Subset: IM |
Affiliation:
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Vanderbilt University Medical Center, Nashville, TN 37232, USA. jessica.l.young@vanderbilt.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Alcohol-Related Disorders / drug therapy, epidemiology Analgesics, Opioid / administration & dosage, adverse effects, therapeutic use* Buprenorphine / administration & dosage, therapeutic use* Child Comorbidity Delivery, Obstetric / methods Female Humans Infant, Newborn Methadone / administration & dosage, therapeutic use* Neonatal Abstinence Syndrome / drug therapy, prevention & control* Opiate Substitution Treatment / methods Opioid-Related Disorders / diagnosis, drug therapy*, epidemiology Pain Management / methods Pregnancy Pregnancy Complications / diagnosis, drug therapy*, epidemiology Prenatal Care / methods, organization & administration Prenatal Exposure Delayed Effects Prescription Drugs / adverse effects Self Medication Substance Withdrawal Syndrome / prevention & control United States / epidemiology |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Opioid; 0/Prescription Drugs; 52485-79-7/Buprenorphine; 76-99-3/Methadone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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