Document Detail

Treatment of a nonhealing saphenous vein harvest graft with treprostinil sodium.
MedLine Citation:
PMID:  18355483     Owner:  NLM     Status:  MEDLINE    
Impaired healing of saphenous vein harvest sites is a serious but under-recognized complication of coronary artery bypass grafting surgery, particularly in the presence of peripheral arterial disease. We report the use of a continuous subcutaneous infusion of treprostinil sodium, an analog of prostacyclin, to treat a limb-threatening, nonhealing saphenous vein harvest incision site after myocardial revascularization.
Dianne Zwicke; Brian Buggy; Don Lobacz; Kristan Rollins; Deborah Strootman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  85     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-21     Completed Date:  2008-04-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  e20-2     Citation Subset:  AIM; IM    
Comprehensive Cardiovascular Care Group, Milwaukee, Wisconsin 53215, USA.
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MeSH Terms
Arterial Occlusive Diseases / complications
Coronary Artery Bypass / adverse effects,  methods*
Coronary Disease / diagnosis,  etiology,  surgery*
Epoprostenol / administration & dosage,  analogs & derivatives*
Infusions, Intravenous
Injections, Subcutaneous
Peripheral Vascular Diseases / complications
Postoperative Complications / diagnosis,  drug therapy
Risk Assessment
Saphenous Vein / transplantation*
Tissue and Organ Harvesting / adverse effects,  methods
Treatment Outcome
Wound Healing / drug effects*
Wounds and Injuries / drug therapy*,  etiology
Reg. No./Substance:
0/treprostinil; 35121-78-9/Epoprostenol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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