Document Detail

Treatment of neurologic complications of antiphospholipid antibody syndrome.
MedLine Citation:
PMID:  8902785     Owner:  NLM     Status:  MEDLINE    
Thrombosis associated with antiphospholipid antibodies (aPL) occurs in both venous and the arterial circulation. The most common arterial thrombo-occlusive event is cerebral infarction. We briefly review treatment strategies aimed at patients with cerebrovascular disease and aPL. Besides general treatment issues, we discuss primary prevention and secondary prevention. Most regimens include antithrombotics or immune modulation. Prospective studies (currently underway) are required to better estimate the rate of recurrent thrombo-occlusive events on standardized therapy before one therapy can be recommended over another with reasonable evidence.
R L Brey; S R Levine
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Lupus     Volume:  5     ISSN:  0961-2033     ISO Abbreviation:  Lupus     Publication Date:  1996 Oct 
Date Detail:
Created Date:  1997-02-12     Completed Date:  1997-02-12     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9204265     Medline TA:  Lupus     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  473-6     Citation Subset:  IM    
Department of Medicine, University of Texas Health Science Center, San Antonio 78284-7883, USA.
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MeSH Terms
Antiphospholipid Syndrome / complications*
Brain Ischemia / prevention & control*

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