| Treatment of necrotizing pancreatitis. | |
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MedLine Citation:
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PMID: 22610008 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Acute pancreatitis is a common and potentially lethal disease. It is associated with significant morbidity and consumes enormous health care resources. Over the last two decades, the treatment of acute pancreatitis has undergone fundamental changes based on new conceptual insights and evidence from clinical studies. The majority of patients with necrotizing pancreatitis have sterile necrosis, which can be successfully treated conservatively. Emphasis of conservative treatment is on supportive measures and prevention of infection of necrosis and other complications. Patients with infected necrosis generally need to undergo an intervention, which has shifted from primary open necrosectomy in an early disease stage to a step-up approach, starting with catheter drainage, if needed followed by minimally invasive surgical or endoscopic necrosectomy once peripancreatic collections have sufficiently demarcated. This review provides an overview of current standards for conservative and invasive treatment of necrotizing pancreatitis. |
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Authors:
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Sandra van Brunschot; Olaf J Bakker; Marc G Besselink; Thomas L Bollen; Paul Fockens; Hein G Gooszen; Hjalmar C van Santvoort; |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-17 |
Journal Detail:
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Title: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association Volume: - ISSN: 1542-7714 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101160775 Medline TA: Clin Gastroenterol Hepatol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 AGA Institute. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Dept. of Operating Theatres and Evidence-Based Surgery, Radboud University Nijmegen Medical Center. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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