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Treatment of necrotizing enterocolitis with probiotics.
MedLine Citation:
PMID:  23101684     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Necrotizing enterocolitis (NEC) is a devastating condition characterized by diffuse intestinal inflammation and necrosis in preterm infants. It is the most common gastrointestinal emergency in the neonatal intensive care unit and is associated with significant morbidity and mortality. Primary risk factors include prematurity and low birth weight. Although the pathogenesis of NEC is complex and not entirely understood, it is known that an interplay between immature intestinal immune responses and the process of bacterial colonization is required for the development of this disease.
Authors:
Kriston Ganguli; W Allan Walker
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Publication Detail:
Type:  Journal Article     Date:  2012-10-05
Journal Detail:
Title:  Gastroenterology clinics of North America     Volume:  41     ISSN:  1558-1942     ISO Abbreviation:  Gastroenterol. Clin. North Am.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-10-29     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8706257     Medline TA:  Gastroenterol Clin North Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  733-46     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Mucosal Immunology Laboratory, Division of Pediatric Gastroenterology, Massachusetts General Hospital for Children, Harvard Medical School, 114 16th Street, Charlestown, MA 02129-4404, USA. Electronic address: kganguli@partners.org.
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