Document Detail


Treatment of mild to moderate facial melasma with the lumixyl topical brightening system.
MedLine Citation:
PMID:  22527440     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background: Melasma is a cutaneous disorder associated with an overproduction of melanin by the tyrosinase enzyme. A proprietary oligopeptide (LumixylTM) was previously shown to competitively inhibit mushroom and human tyrosinase in vitro without the associated cytotoxicity of hydroquinone and to diminish the appearance of facial melasma. Objective: The aim of this case study was to determine if the Lumixyl Topical Brightening System (0.01% oligopeptide cream, an antioxidant cleanser, 20% glycolic acid lotion and physical sunscreen) accelerates clearance of mild-to-moderate melasma. Results: All patients showed improvement in their facial melasma with 1 of 4 patients showing complete clearance after just 6 weeks. Conclusions: Results suggest that this regimen may be a useful new tool to treat mild to moderate melasma. J Drugs Dermatol. 2012;11(5):660-662.
Authors:
Basil M Hantash; Felipe Jimenez
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of drugs in dermatology : JDD     Volume:  11     ISSN:  1545-9616     ISO Abbreviation:  J Drugs Dermatol     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-04-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101160020     Medline TA:  J Drugs Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  660-2     Citation Subset:  IM    
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