| Treatment of migraine headaches with sumatriptan in pregnancy. | |
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MedLine Citation:
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PMID: 15316107 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To review the literature for treatment of migraine headaches with sumatriptan during pregnancy. DATA SOURCES: Studies and reports were located in International Pharmaceutical Abstracts (1970-September 2003) and MEDLINE (1966-week 3 September 2003). DATA SYNTHESIS: Research has been performed to evaluate the risk of teratogenesis after sumatriptan exposure in pregnant patients. Data have been collected in areas including placental transmission of sumatriptan, prospective pregnancy registries, open-labeled and controlled prospective studies, and a retrospective prescription-linked study. As of August 6, 2004, no randomized controlled trials have been conducted with exposure to sumatriptan during pregnancy. CONCLUSIONS: Teratogenesis occurs in approximately 150 000 births per year which represents an incidence of 3-5%. Available literature to date indicates that exposure to sumatriptan during pregnancy has no additional risk of birth defects compared with the incidence in the general population. |
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Authors:
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Michelle L Hilaire; L Brian Cross; Samantha F Eichner |
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Publication Detail:
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Type: Journal Article; Review Date: 2004-08-17 |
Journal Detail:
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Title: The Annals of pharmacotherapy Volume: 38 ISSN: 1060-0280 ISO Abbreviation: Ann Pharmacother Publication Date: 2004 Oct |
Date Detail:
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Created Date: 2004-09-17 Completed Date: 2004-12-22 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9203131 Medline TA: Ann Pharmacother Country: United States |
Other Details:
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Languages: eng Pagination: 1726-30 Citation Subset: IM |
Affiliation:
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University of Tennessee Family Practice Center, Memphis, TN, USA. mhilaire@utmem.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Drug-Induced
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etiology Clinical Trials as Topic Female Humans Migraine Disorders / drug therapy* Pregnancy Pregnancy Complications, Cardiovascular / drug therapy* Pregnancy Outcome Risk Factors Serotonin Agonists / adverse effects*, therapeutic use Sumatriptan / adverse effects*, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Serotonin Agonists; 103628-46-2/Sumatriptan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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