Document Detail


Treatment of melasma by low-fluence 1064 nm Q-switched Nd:YAG laser.
MedLine Citation:
PMID:  23030603     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Low-fluence 1064 nm Q-switched Nd:YAG laser has recently been shown to be effective for the melasma treatment.
OBJECTIVE: The purpose of this study is to evaluate the clinical efficacy and safety of low-fluence 1064 nm Q-switched Nd:YAG laser treatment of melasma in Asian patients.
METHODS: Fifty patients with melasma underwent 15 weeks of weekly treatments, using a Q-switched Nd:YAG laser (RevLite®; HOYA ConBio®, Freemont, CA, USA) at 1064 nm with an 8-mm spot size, and a fluence of 2.8 J/cm(2). Patients and investigators subjectively evaluated the intensity of pigmentation after completion of 15 weekly treatments. The objective assessment was also performed with digital photographs and a pigment imaging tool (Janus®, PSI Co., Ltd., KOREA).
RESULTS: Both patients and investigators rated the treatment outcome as "good improvement" on average with improvement rate of 50-74%. The pigment imaging technology system also confirmed the improvement of the pigmentation level on all three locations of the face. None of the 50 patients showed any signs of severe side effects during the course of the treatment.
CONCLUSION: Low-fluence 1064 nm Q-switched Nd:YAG laser is an effective method to treat melasma without serious side effects in Asian patients.
Authors:
Ji Hoon Sim; Young Lip Park; Jong Suk Lee; Sung Yul Lee; Won Bok Choi; Hyun Jo Kim; Jung Hoon Lee
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-02-24
Journal Detail:
Title:  The Journal of dermatological treatment     Volume:  25     ISSN:  1471-1753     ISO Abbreviation:  J Dermatolog Treat     Publication Date:  2014 Jun 
Date Detail:
Created Date:  2013-12-16     Completed Date:  2014-04-01     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  8918133     Medline TA:  J Dermatolog Treat     Country:  England    
Other Details:
Languages:  eng     Pagination:  212-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Asian Continental Ancestry Group
Female
Humans
Laser Therapy, Low-Level*
Lasers, Solid-State / therapeutic use*
Melanosis / radiotherapy*
Middle Aged
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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