| Treatment of melanoma-associated retinopathy. | |
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MedLine Citation:
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PMID: 20842490 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OPINION STATEMENT: Melanoma-associated retinopathy is a rare paraneoplastic disorder that is challenging to diagnose and even more difficult to treat. Because of the rarity of the disease, therapy is based on analysis of case series and case reports. Based on evidence from these reports, first-line therapy is cytoreduction of metastatic disease through metastasectomy, chemotherapy, and radiation. This can be combined with intravenous immunoglobulin. For refractory visual symptoms, additional therapies include systemic corticosteroids and plasmapheresis, but the success of these strategies has been limited. Because of the rarity of the disorder, new therapies should be evaluated and reported in the literature to expand our clinical understanding of this autoimmune disease. |
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Authors:
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Steven F Powell; Arkadiusz Z Dudek |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current treatment options in neurology Volume: 12 ISSN: 1534-3138 ISO Abbreviation: Curr Treat Options Neurol Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-09-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9815940 Medline TA: Curr Treat Options Neurol Country: United States |
Other Details:
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Languages: eng Pagination: 54-63 Citation Subset: - |
Affiliation:
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Department of Medicine, Division of Hematology, Oncology, and Transplantation, University of Minnesota Medical School, MMC 480, 420 Delaware Street SE, Minneapolis, MN, 55455, USA. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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