Document Detail

Treatment of lumbar disks with chymopapain.
MedLine Citation:
PMID:  1265109     Owner:  NLM     Status:  MEDLINE    
Symptoms arising from a herniated disk appear when the nucleus pulposus or soft inner portion of the disk bulges against a nerve root. When conservative treatment fails to help the patient, the enzyme chymopapain is currently being used in the treatment of such conditions. Injected directly into the disk, the chymopapain dissolves the nucleus by enzymatic action which selectively breaks certain bonds within the nucleus. The pressure within the center is decreased, hence the pressure against the nerve root is relieved, alleviating the symptoms. Because back care is particularly important following such treatment, physical therapy is valuable in promoting continued relief. The major emphasis of the therapy back care program is on abdominal strengthening exercises and postural training.
J E Dunn; C L Johnson; W Cox
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physical therapy     Volume:  56     ISSN:  0031-9023     ISO Abbreviation:  Phys Ther     Publication Date:  1976 Apr 
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0022623     Medline TA:  Phys Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  399-402     Citation Subset:  AIM; IM    
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MeSH Terms
Chymopapain / administration & dosage,  adverse effects,  therapeutic use*
Endopeptidases / therapeutic use*
Intervertebral Disk Displacement / drug therapy*,  therapy
Physical Therapy Modalities
Reg. No./Substance:
EC 3.4.-/Endopeptidases; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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