| Treatment of life-threatening primary pulmonary hemosiderosis with cyclophosphamide. | |
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MedLine Citation:
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PMID: 1516434 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This report describes a five-year-old boy with severe pulmonary hemorrhage caused by primary pulmonary hemosiderosis with cow's milk sensitivity. After failing to respond to corticosteroids and azathioprine, he dramatically improved after being given cyclophosphamide. He worsened after discontinuation of cyclophosphamide on two occasions and improved significantly with its reinstitution. Cyclophosphamide was continued for 14 months without further bleeding or adverse effects. The patient has remained in remission for nearly five years. Cyclophosphamide may be a life-saving alternative therapy for refractory pulmonary hemorrhage with pulmonary hemosiderosis. |
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Authors:
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J L Colombo; S M Stolz |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Chest Volume: 102 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1992 Sep |
Date Detail:
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Created Date: 1992-10-07 Completed Date: 1992-10-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 959-60 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics, University of Nebraska Medical Center, Omaha 68198-5190. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Child, Preschool Cyclophosphamide / therapeutic use* Hemoptysis / etiology Hemosiderosis / complications, drug therapy* Humans Lung Diseases / complications, drug therapy* Male Milk Hypersensitivity / complications Syndrome |
| Chemical | |
Reg. No./Substance:
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50-18-0/Cyclophosphamide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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