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Treatment of lepromatous ulcers using citric acid as a sole antimicrobial agent.
MedLine Citation:
PMID:  22264346     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A prospective study was carried out to assess the role of citric acid as a sole antimicrobial agent in the management of lepromatous ulcers. Thirty-four known cases of lepromatous ulcers not responding to conventional antibiotic therapies for long duration were investigated for culture and susceptibility studies. Staphylococcus aureus (25·00%) and Klebsiella spp. (23·43%) were found to be the most common isolates. Amikacin (68·75%) and ciprofloxacin (67·18%) were found to be the most effective antimicrobial agents. Topical application of citric acid ointment resulted in complete healing in 25 (73·52%) cases. In eight cases (26·48%), there was elimination of infective agent from ulcer site and formation of healthy granulation, but no complete healing of ulcer was seen. Results indicate that citric acid is the best alternative for the effective management of lepromatous ulcers when other therapies are exhausted.
Authors:
Basavraj S Nagoba; Bharat J Wadher; Arunkumar Rao; Sohan P Selkar; Rajan C Gandhi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-20
Journal Detail:
Title:  International wound journal     Volume:  -     ISSN:  1742-481X     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101230907     Medline TA:  Int Wound J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors. © 2012 Blackwell Publishing Ltd and Medicalhelplines.com Inc.
Affiliation:
BS Nagoba, PhD, Assistant Dean (R&D) and Professor of Microbiology, MIMSR Medical College and YCR Hospital, Latur, Maharashtra, India BJ Wadher, PhD, Medical Microbiology Research Laboratory, P. G. Department of Microbiology, RTM Nagpur University, Nagpur, Maharashtra, India A Rao, MS, Department of Orthopedics, MIMSR Medical College and YCR Hospital, Latur, Maharashtra, India SP Selkar, MPhT, MIP College of Physiotherapy, Latur, Maharashtra, India RC Gandhi, MS, Department of Surgery, MIMSR Medical College and YCR Hospital, Latur, Maharashtra, India.
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