| Treatment of left main and multivessel disease in the drug-eluting stent era. | |
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MedLine Citation:
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PMID: 19898278 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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For decades, the established standard of care for left main and multivessel coronary artery disease has been coronary artery bypass surgery because a significant survival advantage was found in patients revascularized with surgery compared with medical management. Although visions of less invasive strategies to manage this disease arose with the development of percutaneous coronary interventions, surgery proved to provide higher survival rates compared with balloon angioplasty and improved durability, with fewer required repeat revascularizations, compared with use of bare-metal stents. Drug-eluting stents revived hopes of an alternative treatment modality after trials demonstrated their safety and efficacy in other types of high-risk patients. Their wide-spread on- and off-label use led to several nonrandomized studies and, more recently, to randomized clinical trials comparing drug-eluting stents and bypass surgery. |
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Authors:
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Vivian G Ng; Alexandra J Lansky |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Reviews in cardiovascular medicine Volume: 10 Suppl 2 ISSN: 1530-6550 ISO Abbreviation: Rev Cardiovasc Med Publication Date: 2009 |
Date Detail:
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Created Date: 2009-11-09 Completed Date: 2010-11-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100960007 Medline TA: Rev Cardiovasc Med Country: United States |
Other Details:
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Languages: eng Pagination: S24-33 Citation Subset: IM |
Affiliation:
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Columbia University Medical Center and The Cardiovascular Research Foundation, New York, NY, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Balloon, Coronary
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adverse effects,
instrumentation*,
mortality Coronary Artery Bypass Coronary Artery Disease / diagnosis, mortality, therapy* Drug-Eluting Stents* Evidence-Based Medicine Humans Patient Selection Prosthesis Design Risk Assessment Severity of Illness Index Time Factors Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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