Document Detail

Treatment of keloid sternotomy scars with 585 nm flashlamp-pumped pulsed-dye laser.
MedLine Citation:
PMID:  7739306     Owner:  NLM     Status:  MEDLINE    
Despite increasing knowledge of wound healing and collagen metabolism, hypertrophic scars and keloid scars are difficult to eradicate. Median sternotomy scars are often hypertrophic or keloidal. We treated them with a 585 nm flashlamp-pumped pulsed-dye laser, which selectively injures cutaneous microvessels without inducing scars. 16 adult patients with hypertrophic or keloidal median sternotomy scars after heart surgery received two treatments to one half of their previously untreated scars every 6-8 weeks and were reviewed at 6 months. Symptoms and clinical, histological, photographic, and surface texture assessments were obtained for treated and untreated areas of scar and evaluated independently by two observers blind to the treatment and by digital image analysis of skin surface casts. There was a significant improvement in erythema, scar height, skin surface texture, and pruritus in laser-treated scar areas; this improvement persisted for at least 6 months.
T S Alster; C M Williams
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Lancet     Volume:  345     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-06-07     Completed Date:  1995-06-07     Revised Date:  2009-02-26    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1198-200     Citation Subset:  AIM; IM    
Department of Medicine, Georgetown University Medical Center, Washington, DC, USA.
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MeSH Terms
Cicatrix, Hypertrophic / etiology,  therapy*
Keloid / etiology,  therapy*
Laser Therapy*
Middle Aged
Postoperative Complications / therapy*
Sternum / surgery
Treatment Outcome

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