Document Detail

Treatment of intracranial atherosclerotic arterial stenoses with a balloon-expandable cobalt chromium stent (Coroflex Blue): procedural safety, efficacy, and midterm patency.
MedLine Citation:
PMID:  19921164     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: We evaluated the coronary balloon-expandable cobalt chromium stent Coroflex Blue for the treatment of intracranial atherosclerotic arterial stenoses (IAAS). METHODS: Between March 2007 and October 2007, a total of 25 patients (20 male, age median 67 years) with 30 IAAS underwent endovascular treatment using Coroflex Blue stents (B. Braun, Germany). Location and degree of target stenoses before and after treatment and at follow-up and adverse clinical sequelae of treatment were registered. Angiographic follow-up was scheduled for 6, 12, 26, and 52 weeks after the treatment. RESULTS: The 30 treated lesions were located as follows: nine in intracranial-extradural internal carotid artery (ICA), three in intradural ICA, five in middle cerebral artery, eight in intradural vertebral artery, and five in basilar artery. The technical success rate was 100%. The degree of stenoses prior to and after treatment was 61 +/- 2% and 26 +/- 3% (mean +/- SE), respectively. A residual stenosis of <50% was achieved in 29 (97%) procedures. Treatment was uneventful in 28 out of 30 procedures (93%); one patient suffered a transient and one patient a permanent neurological deficit. Angiographic follow-up was available in all of the patients (100%) after 15.2 months (median) and showed significant (i.e., more than 50%) degree of recurrent stenosis in 11 (37%) of the lesions. Retreatment was performed in 11 (37%) lesions. CONCLUSION: The Coroflex Blue stent is easily inserted and safely deployed into intracranial arteries. The incidence of recurrent stenoses remains a concern. Stringent angiographic and clinical follow-up and retreatment are therefore mandatory.
Zsolt Vajda; Elina Miloslavski; Thomas Güthe; Elisabeth Schmid; Christoph Schul; Guido Albes; Hans Henkes
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2009-11-17
Journal Detail:
Title:  Neuroradiology     Volume:  52     ISSN:  1432-1920     ISO Abbreviation:  Neuroradiology     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-25     Completed Date:  2010-10-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1302751     Medline TA:  Neuroradiology     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  645-51     Citation Subset:  IM    
Klinik für Neuroradiologie, Katharinenhospital-Klinikum Stuttgart, Kriegsbergstrasse 60, 70174, Stuttgart, Germany.
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MeSH Terms
Angioplasty, Balloon / instrumentation*,  methods
Carotid Stenosis / pathology,  therapy*
Cerebral Angiography
Cerebral Arterial Diseases / pathology,  therapy*
Chromium Alloys
Follow-Up Studies
Intracranial Arteriosclerosis / pathology,  therapy*
Postoperative Complications
Stents* / adverse effects
Time Factors
Treatment Outcome
Vertebrobasilar Insufficiency / pathology,  therapy*
Reg. No./Substance:
0/Chromium Alloys
Comment In:
Neuroradiology. 2010 Jul;52(7):653-4   [PMID:  20502889 ]

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