Document Detail

Treatment of interstitial pregnancy with methotrexate: report of an unsuccessful case.
MedLine Citation:
PMID:  7989525     Owner:  NLM     Status:  MEDLINE    
Until now, the traditional management of interstitial pregnancy has been surgical. Lately, we have advocated conservative treatment with methotrexate as an option for infertility patients. This is the first publication of a rupture with abundant intra-abdominal bleeding during systemic treatment with methotrexate of a patient with an interstitial pregnancy. Signs of therapy failure are discussed.
R R Voigt; F van der Veen; V H Karsdorp; H V Hogerzeil; B W Ketting
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  9     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1994 Aug 
Date Detail:
Created Date:  1995-01-12     Completed Date:  1995-01-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1576-9     Citation Subset:  IM    
Department of Obstetrics and Gynaecology, Academic Medical Centre, Amsterdam, The Netherlands.
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MeSH Terms
Chorionic Gonadotropin / blood
Methotrexate / administration & dosage,  therapeutic use*
Pregnancy, Ectopic / drug therapy*,  surgery,  ultrasonography
Rupture, Spontaneous
Reg. No./Substance:
0/Chorionic Gonadotropin; 59-05-2/Methotrexate
Comment In:
Hum Reprod. 1995 May;10(5):1273-4   [PMID:  7657777 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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