| Treatment of interstitial cystitis with immunosuppression and chloroquine derivatives. | |
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MedLine Citation:
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PMID: 971677 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Azathioprine, an immunosuppressive agent, was given to 38 patients presenting with intestinal cystitis. Pain disappeared completely in 22 patients and pollakiuria did the same in 20 patients, including two very severe cases with very contracted bladder. Chloroquine or oxychloroquine, usually combined with salicylate, was given to 22 patients. Pain disappeared in 11 patients and pollakiuria in 4 patients. No effect was noted in 10 patients in the azathioprine group and in 8 patients in the chloroquine group. The remaining patients had partial alleviation. The results are analyzed separately for various grades of severity. Spontaneous cure can be expected only in 11% of cases of interstitial cystitis calculated from a large series. Immunosuppression or chloroquine derivates are indicated for patients who do not respond to other treatments. |
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Authors:
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K J Oravisto; O S Alfthan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: European urology Volume: 2 ISSN: 0302-2838 ISO Abbreviation: Eur. Urol. Publication Date: 1976 |
Date Detail:
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Created Date: 1976-12-03 Completed Date: 1976-12-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7512719 Medline TA: Eur Urol Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 82-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Autoimmune Diseases
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drug therapy* Azathioprine / administration & dosage, therapeutic use* Chloroquine / administration & dosage, analogs & derivatives*, therapeutic use* Cystitis / drug therapy*, pathology Drug Administration Schedule Humans Urinary Bladder / pathology |
| Chemical | |
Reg. No./Substance:
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446-86-6/Azathioprine; 54-05-7/Chloroquine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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